Neural Stem Cells as Potential Glioblastoma Cells of Origin
Glioblastoma multiforme (GBM) is the most malignant brain tumor in adults and it remains incurable.These tumors are very heterogeneous, resistant to cytotoxic therapies, and they show high rates of invasiveness.Therefore, patients face poor prognosis, and the survival rates remain very low.Previous research states that GBM contains a cell populatio